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Mức giảm nhanh hơn khi cơ thể phải xử lý nhiều tác nhân oxy hóa cùng lúc, chẳng hạn tia UV, khói bụi, rượu bia, thiếu ngủ kéo dài hoặc khẩu phần nghèo rau xanh

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Furthermore, immune dysfunction appears to extend to the PB, BM and spleen