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In addition, MPO secreted by TANs can catalyze the production of hypochlorous acid (HOCl) from H 2 O 2 and Cl⁻, which directly oxidizes tumor cell membrane lipids, resulting in a 4-fold increase in lipid peroxidation and accelerating the ferroptosis process

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[DOI] [PubMed] [Google Scholar] [7].Bartesaghi S, Radi R, Fundamentals on the biochemistry of peroxynitrite and protein tyrosine nitration, Redox Biol