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A UAE-based case-control study reported lower SOD activity, increased LPO, and elevated homocysteine levels in women with PCOS, with these findings correlating with age, body mass, and disease duration (47)
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The data discussed here summarize some of the roles of endogenous estrogens, estrogen-based therapies, and estrogen-like molecules on brain homeostasis, particularly in neurogenesis, gliogenesis, and regulation of the neuroprotection/neurodegeneration balance
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