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This continues to correspond with the conflicting pro-development (Akt)/ development attenuation (GSK-3) relationship, which may be a direct link to the mTOR complex 1's (mTORC1) ability to increase ribosomal DNA transcription, which indicates increased ribosomes

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We reasoned that introducing a leucine zipper motif to the C-terminus of c-MET927 with a short flexible loop (denoted as c-MET927-LZ) could potentially stabilize the c-MET/HGF complex in the active state (Fig