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on the other side, p53 directly inhibits the activity of DPP4 or induces the expression of CDKN1A/p21, to make it difficult for NOX1 to interact with DPP4 to form complexes, thus alleviating lipid peroxidation and ferroptosis (Tao et al., 2020)

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LXRα also greatly impacts resetting the clock properties in the male mice

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