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Concomitantly, as shown in animal models of catabolic stress, glutamine-using tissues including the gut, kidney, and immune cells markedly increase their uptake and metabolism of glutamine (1, 6, 7, 9, 11, 14, 15, 16, 46)

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For some patients, a single infusion is entirely appropriate for an acute period of depletion, such as recovery from an illness or an unusually demanding stretch of physical activity