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Other author suggest that lactic acid reduces the activity of NF-κB and the expression of pro-inflammatory cytokines presenting anti-inflammatory effects in LPS-stimulated macrophages through of GPR81 (110, 111)
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PACK:Progress - Pack of 2 (40 Tabs)
Overall, while the cellular pathways of L -2HG metabolism remain incompletely understood, the impairment of L2HGDH clearly plays a central role in disease progression
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