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Research has demonstrated that administering glutathione intravenously twice a week for 60 days can lead to a reduction in symptoms and even potentially slow the progression of Parkinson’s disease in patients

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The pharmaceutical industry abandoned GH secretagogue development in the early 2010s not because the compounds don't work—Phase 3 trials consistently demonstrated GH and IGF-1 elevation—but because the therapeutic window for meaningful clinical outcomes (muscle preservation in cachexia, bone density improvement in osteoporosis) was too narrow relative to metabolic side effects like glucose intolerance