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For ADCs such as Mylotarg, Blenrep, Trodelvy, and Camidanlumab, the future lies in creating more stable, tumor-specific linkers, site-specific conjugation for consistent DAR, and next-generation payloads with improved therapeutic windows, while bispecific ADCs and immune-modulating payloads are also advancing

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[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Hou G.-X., Liu P.-P., Zhang S., Yang M., Liao J., Yang J., Hu Y., Jiang W.-Q., Wen S., Huang P