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FTIR and Raman spectroscopy serve as spectroscopic fingerprints to identify interaction-induced vibrational shifts

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In general, upon binding Tau protects MTs from depolymerization and is highly likely to be a factor in the induction of MT polymerization (Barbier et al., 2019), thus playing a key role in MT dynamics and resulting in increased MT growth rates and reduced dissociation rates (Murphy et al., 1977