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The research showed that the concentration of 0.05% NaHCO 3 increased the DCI content in the sprouts of Tartary buckwheat by up to 9-fold (40), and metal ions (Al 3+ , Cu 2+ , Zn 2+ ) also could increase α-glycosidase activity to release more free DCI, so as to increase the effect of reducing sugar in buckwheat (41)

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The two work through opposite logics: tretinoin drives forced epidermal turnover via retinoic acid receptors, while GHK-Cu promotes gentle matrix remodeling and repair through gene modulation