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In acute myeloid leukemia, the m6A methyltransferase METTL3 and the reader protein IGF2BP3 maintain high-level serine synthesis by recognizing and stabilizing the mRNAs of SSP-related genes including ATF4, PHGDH and PSAT1, meeting the high metabolic demands of cancer cells, particularly leukemia stem/initiating cells (93)

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Tendon and Ligament Regeneration Preclinical research has shown BPC-157 accelerates tendon-to-bone healing and increases the organization of collagen fibers