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[41] [42] Second trimester and later [edit] Warfarin administration in the second and third trimesters is much less commonly associated with birth defects, and when they do occur, are considerably different from FWS

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“Open-label studies, where everyone knows they’re getting the treatment, commonly show promising effects that reflect expectations rather than treatment effectiveness.” Wang went on to warn that certain results of the study are not consistent and require further research.