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Natural approaches for the management of ulcerative colitis: evidence of preclinical and clinical investigations - PMC

Preclinical models report tendon, ligament, muscle, and gut healing benefits, but human evidence remains limited to a handful of small open-label pilot studies

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The protective effects were diminished upon SLC7A11 knockout, indicating that GAL mitigates ferroptosis and neuronal cell death by enhancing the SLC7A11/GPX4 pathway (Guan et al., 2021)