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GSH and pyroptosis Pyroptosis is a form of lytic cell death characterized by gasdermin-mediated plasma membrane pore formation, leading to osmotic swelling, membrane rupture, and the release of mature pro-inflammatory cytokines, including interleukin 1 beta (IL1B, also known as IL-1β) and interleukin 18 (IL18)

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3 Results 3.1 In vitro enzymatic activity and antioxidant assays of PFE As the ratio of PCR to FA in the PFE might affect the pharmacological evaluations, we first screened for the optimal ratio of PCR to FA