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reported that GDF11 did not save the pathologic myocardial hypertrophy associated with aging but accelerated the aging process (36)
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In erythroleukemia K562 cells, in addition to the above identified NRF2 binding ARE motif, there is also a strong association of active histone codes (such as H3K4Me3, H3K9Ac, H3K27Ac, H3K79Me2) upstream of the transcription start site (Supplementary Fig
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