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Do you follow a vegan diet? Did you know that vitamin b12 is mainly present in animal-based products so those following a strict plant-based are more likely to be deficient in vitamin
In addition to oligonucleotide therapeutics, some small-molecule NNMT inhibitors have been reported recently [56–59] and several have shown effectiveness in the prevention or treatment of obesity and T2D in vitro [60, 61] or in preclinical animal models [10, 58, 62], validating NNMT as a pharmacological drug target
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This could be due to the lack of intrinsic factors, a protein in the stomach required for the absorption of this essential vitamin
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