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Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNFα) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)

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However, if the lump grows, becomes extremely painful, shows signs of infection like spreading redness or warmth, or persists longer than three weeks, contact your healthcare provider to rule out complications