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It is a useful reminder that not every deviation from a native sequence is a potency argument, and that reading a modification correctly requires knowing what it was for

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Common examples include fatigue or low energy with normal blood results, brain fog or reduced concentration without confirmed vitamin B12 deficiency, stress-related exhaustion or burnout, increased metabolic demand such as during illness recovery, high workload, or intense training, restrictive or inconsistent dietary intake, or suspected poor oral absorption despite normal serum levels