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Its efficient chemical conjugation with another Cys-functional protein, through a single carbon atom as a linker, showcases the potential of our method to recombinatorily generate protein-protein constructs in a fully site-selective manner from native proteins and with complete selectivity for the heterodimer, as demonstrated by LC-MS and SDS-PAGE analysis (see Figs

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JS: Conceptualization, Formal Analysis, Writing – original draft