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A second cohort of mice including WT, RAMP1 KO, RAMP3 KO, and RAMP1/3 KO genotypes confirmed that both RAMP1 and RAMP3 are individually essential for a full cagrilintide-induced neuronal activation response

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Further investigation should focus on enhancing the stability and efficacy of topical or oral antioxidant products against hyperpigmentation for long-term use