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In turn, an imbalanced microbiome can negatively affect the host’s circadian clock and metabolism ( Importantly, responses to melatonin supplementation and chrononutritional strategies exhibit substantial inter-individual variability among older adults

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Quercetin enhances cisplatin and radiation sensitivity through p53 activation (Vafadar et al., 2020), while ongoing trials, such as NCT05306002, are assessing curcumin’s adjuvant potential in OC