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High levels of Hcy can activate the expression and release of inflammatory factors, leading to vascular endothelial dysfunction ( in vitro studies have corroborated the ability of Hcy to induce the release of inflammatory cytokines from ECs, including interleukin-6, interleukin-8, and tumor necrosis factor-α (Kamat et al., 2013

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Practice Bulletin, 196, 1-18