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However, the concentrations of these conjugates are significantly higher in the substantia nigra of the PD patients, suggesting that these compounds may contribute to the damage in this region of the brain in PD patients (Spencer et al., 1998)

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A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes