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Moreover, the probiotics Lactobacillus acidophilus and Bifidobacterium bifidum were found to decrease the expression of miR-18a in CRC (149)

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For example, in a recent randomized, cross-over intervention, administration of PEITC (40 mg/day for five days) caused a modest, yet significant, 7.7% reduction in the metabolic activation of the tobacco-specific lung carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, in cigarette smokers (60)