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In secondary hypothyroidism Either, insufficient TSH is produced, and thus the thyroid gland does not produce sufficient T3 and T4 Or, the thyroid gland has been removed or damaged surgically, or by radiotherapy or another process, and thus is unable to produce sufficient T3 and T4 It is crucial to understand this process to be able to interpret thyroid function test blood results

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In the BHMT pathway, Hcy uses betaine as a methyl donor, ultimately producing methionine and dimethylglycine (DMG)