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BH4 availability is largely driven by the Mg 2+ , Zn 2+ , and NADPH dependent de novo synthesis pathway composed of the rate limiting enzyme GTP cyclohydrolase I (GCH1) together with 6-pyruvoyl-tetrahydropterin synthase and sepiapterin reductase

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Für den praktizierenden Kampfsportler gilt jedoch: Die Spreu trennt sich vom Weizen — evidenzbasierte, zugelassene und qualitativ geprüfte Anwendungen (beispielsweise bestimmte Kollagenpeptide) unterscheiden sich grundlegend von experimentellen, regulatorisch nicht zugelassenen Substanzen (etwa viele Wundheilungs-Peptide oder Secretagoge-Kombinationen)