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Although CD38 high NK cell population is reduced by CD38 mAb, it brings few destructive effects to the efficacy and safety during combined therapy, because IMiDs, such as Lenalidomide, markedly enhance NK cell-mediated ADCC by increasing the number and activity of activated CD16 + NK cells [71, 98, 101]
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Sometimes I think that it would be more appropriate to keep the plug of the rain barrel open at all times, so that even on the days in which the rain barrel is overwhelmed by a cascade of water from a big, torrential storm, the rain water can flow through it, and soften and dissipate into the packed Earth below and also evaporate into the ocean of air surrounding it