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Spirulina is made up of polysaccharides that contain many functional groups (e.g., uronic acid and phenolic hydroxyl groups) that participate in the antioxidant and free radical scavenging activities [6] by enhancing the activity of nitric oxide (NO), superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and glutathione peroxidase (GPX) in liver, kidney, and brain tissues [7]

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Our search was carried out without year limitations because there was no previous review article on this topic