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212 There is increasing evidence that inhibition of the NF-κB signaling pathway can alleviate the symptoms of UC and thus play a beneficial therapeutic role
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Strengths:20 MG
Finally, the longest (28-day) Phase I study with BMS-830216, a pharmacological antagonist of MCH signaling (36) produced no indications of weight loss or reduced food intake and the compound did not proceed to Phase II studies
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