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Those in the middle tertile (adjusted OR = 0.48, 95% CI [0.25, 0.93], P = 0.03) and highest tertile (adjusted OR = 0.44, 95% CI [0.22, 0.87], P = 0.02) had much lower chances of testosterone deficiency than men with the lowest B12 levels [5]

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Preclinical research evidence Animal Experiments Obese mouse model: After subcutaneous injection of AOD 9604 (250 μg/kg) daily for 8 weeks, the body weight of obese mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue decreased significantly