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Shown are the frequencies of ( b ) CD45 + cells, ( c ) macrophages, ( d ) M1-like macrophages, ( e ) M2-like macrophages in tumors, and ( f ) CD3 + CD45 + T cells, ( g ) CD8 + CD3 + T cells in the tdLNs, ( h ) the number of AH1-specific CD8 + T cells in tumor

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This has led to the idea of “pimple patterns, ” where specific spots on the face might be linked to different causes, such as diet, stress, or health problems