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[39] In the liver, when ischemia-reperfusion occurs, macrophages alter hepatocyte metabolism (downregulation of FTH and GPX4 and upregulation of ACSL4) and induce ferroptosis by forming lactoferrin-rich extracellular traps and releasing ROS

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Similarly, muscle atrophy induced by cancer cachexia is also preceded by muscle weakness (Delfinis et al., 2022)