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Compounded semaglutide + B12 is a custom-formulated medication and is not the same as the brand-name medication
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Across GLP-1 trials, about 60% of lost weight returns within the first year and roughly 75% returns over the longer curve, with the fastest regain in the early months.²¹ The semaglutide extension follows the same direction.⁶ The pattern reflects removal of appetite suppression after major weight loss
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