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Prepared formulations (n=3) were degassed with bubbling N 2 gas and were filled in light protected ampoules and placed in preheated ovens

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Size:Sterile Water for Injection, 1000ml bag, 12/case - B Braun (Rx)

The 200, 100 and 50 ng/mL of PC spikes signaled above the cut point in the presence of 50 ug/mL of PC, indicating drug tolerance well above the C max value reported for the highest dose of pegadricase administered in the clinical study (Supplementary Fig