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Glutamine Synthetase as a Therapeutic Target for Cancer Treatment
Thus, an improved understanding of the regulation of UA and its neuroprotective action in the human brain will shed further light on neurodegenerative processes and potentially identify novel targets for pharmacotherapeutic intervention
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Here, we determine structures of cagrilintide bound to Gs-coupled, active, amylin receptors (AMY 1 R, AMY 2 R, AMY 3 R) and calcitonin receptor (CTR) and compare cagrilintide interactions and the dynamics of receptor complexes with previously reported structures of receptors bound to rat amylin, salmon calcitonin or recently developed amylin-based peptides
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