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The binding pocket in class A GPCRs is typically deep and narrow, allowing various ligand binding orientations 68,79
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Taille:250 grammes (8,8 onces)
Nucleic acid aptamers are single-stranded DNA or RNA oligonucleotides capable of specifically binding to a wide range of molecules with dissociation constants from the nano- to picomolar range for protein targets and in the micromolar range for smaller molecules