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In the future, more basic and clinical research should be performed to clarify the role of VEGF in tendon healing and to clearly determine the conditions under which VEGF is beneficial for tendon injury, with factors to be considered being the tendon disorder type, stage of tendon healing and inflammation status

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Currently, Setmelanotide is being tested as a therapeutic option for rare genetic disorders of obesity such as POMC deficiency, heterozygous deficiency obesity, and POMC epigenetic disorders (30-32)