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390 Other clinical studies focusing on providing additional drug options for HR+ advanced breast cancer patients following CDK4/6 inhibitor use are currently ongoing within the realm of PI3K/AKT/mTOR pathway inhibitors

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However, available literature suggests that amlodipine may have additional mechanisms of action, including reduction of oxidative stress and protein glycation, which play essential roles in the pathogenesis of cardiovascular diseases 21,22,23