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1 In contrast, in cancer, where malignant cells exploit heightened proteostasis resilience to tolerate genomic instability and therapeutic stress, strategically destabilizing resilience may enhance therapeutic vulnerability

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To date, the administration has approved only a narrow band of initiatives [mostly longstanding Institutions for Mental Diseases (IMD)/Substance Use Disorder (SUD) waivers] while leaning on short temporary extensions of three to 15 months to keep negotiating rather than issuing final decisions