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It should be also noted that positive effects of vitamin B12 on the recovery of the motor and sensory function and nerve regeneration, especially myelination, could also be shown for a new local application, namely, an electrospun nanofiber sheet incorporating methylcobalamin with local delivery [59]
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It is noteworthy that in humans with type 2 diabetes CBD not only did not exhibit enhanced vasodilatory properties (in isolated pulmonary arteries) [48], but CBD vasorelaxant responses were blunted (in mesenteric arteries) [144]