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Since C-terminal residues are known to be involved in the trafficking to lysosome, inclusion of additional residues downstream to the C-terminus was probably affecting its localization

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Unlike longevity compounds (such as NAD+) which you might use daily for years, healing peptides are best utilized in "cycles." You introduce them during a period of trauma, injury, or planned recovery (such as post-surgery) for 4 to 8 weeks, allow the body to heal, and then discontinue use once normal tissue function has returned