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While no overall difference in progression-free survival was observed between dose-dense TMZ and radiotherapy, IDH mutant, 1p/19q codeleted tumors responded more favorably to chemotherapy
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In a randomised controlled trial in community-dwelling subjects, Lewerin found that four months of oral 0.5 mg vitamin B12 in combination with folic acid and vitamin B6 normalised serum MMA and Hcys levels, but failed to improve movement and cognitive performance [37]
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