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This is especially beneficial for those who may struggle to get adequate B12 through diet alone, including vegetarians, vegans, or those with certain digestive issues
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Upon delivery of B12 to the tissues by holo TC, receptor-mediated endocytosis occurs, after which holoTC enters acidic lysosomes where the transcobalamin protein is degraded, the B12 is released, and then converted to its cofactor forms (Allen et al., 2018)
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