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Skincare effect:Healing

Cyss uptake by SLC7A11/xCT induces NRF2 expression and activation Since TNBC cells are known to express high levels of the cystine/glutamate antiporter SLC7A11/xCT, we wondered whether the cellular Cyss uptake and consequently cytoplasmic Cys levels are responsible for the activation of the NRF2 pathway