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Under low-iron conditions, IRPs bind to IREs in the untranslated regions (UTRs) of target mRNAs, stabilizing TfR1 and DMT1 transcripts while suppressing translation of ferritin and FPN1

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In this context, CP may have a beneficial effect on the vascular system, with some clinical studies finding improvements in SBP (Reference Al Hajj, Salla and Krayem13)