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Grade II acute cholangitis Urgent biliary drainage within 24–48 hours of presentation Underlying cause Treat concurrently with biliary drainage (i.e., a single-stage procedure) OR treat electively, after the patient improves with biliary drainage (i.e., a two-stage procedure) Grade III acute cholangitis Urgent biliary drainage within 24 hours of presentation [9] [20] Treat the underlying cause once the patient's condition improves after urgent biliary drainage (i.e., a two-stage procedure) Urgent drainage of infected bile is imperative in order to achieve rapid source control in patients with grade II–III acute cholangitis