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For DSIP : baseline and 4-week actigraphy, a Pittsburgh Sleep Quality Index (PSQI) score at baseline and week 4, and a basic metabolic panel at baseline to assess hepatic function

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Branched chained amino-acids (BCAA) are known to stimulate cell growth by the activation of mTORC2, a protein complex that controls protein synthesis in cells by sensing nutrient and energy availability and is also one of the main signaling pathways of IGF-I and insulin (Figure 3)