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For instance, the breakdown of dietary nutrients such as choline, coupled with lipid metabolism and host immune system modulation, can lead to the development of atherosclerosis ( Beyond metabolic pathways, the gut microbiota also interacts with systemic immunity to influence CVD progression

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However, the presence or episodic reactivation of the virus increases the risk of transforming healthy cells to malignant cells that routinely escape host immune surveillance or of producing pathogenic autoantibodies

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