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These dietary adjustments, provided they are personalized and monitored by healthcare providers, can help maintain nutritional balance despite eating less

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Specifically, administration of high-dose HIF-PHIs or sustained HIF-1 activation was found to exacerbate renal injury ( Malignancy risk Despite the critical role of HIF-mediated hypoxia adaptation in tumor progression, roxadustat phase 3 studies have not shown any signals indicating cancer initiation and/or progression